They can dissociate 3 protons (XDP) or 4 protons (XTP) from their phosphoric acid groups.Phosphoanhydride bonds link second and perhaps third phosphates to the 5’-OH on the ribose moiety Biochemistry: Nucleic Acid Chem&Struct.cAMP and cGMP are the important ones(see previous lecture!) Biochemistry: Nucleic Acid Chem&Struct.3’ and 5’ hydroxyls are both involvedin -O-P-O bonds, forming a 6-membered ring (-C5’-C4’-C3’-O-P-O-).dTTP (= TTP) = deoxythymidylate = thymidylate Biochemistry: Nucleic Acid Chem&Struct.These aromatic rings absorb around 260 Biochemistry: Nucleic Acid Chem&Struct.PKa’s for base N’s and PO4’s Biochemistry: Nucleic Acid Chem&Struct
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